Dysimmune
and Inflammatory Neuropathies

CIDP

Chronic Inflammatory Demyelinating Polyneuropathy

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is the most common treatable chronic neuropathy worldwide, with a prevalence ranging from about 1 to 9 cases per 100 000. CIDP typically presents a relapsing or progressive neuropathy with proximal and distal weakness which develops over at least an 8-week period. CIDP is classed as an autoimmune disorder in which a dysimmune response is directed towards components of the peripheral nerve causing demyelination, Node of Ranvier and/or axonal damages. The exact mechanisms underlying the
development of immunopathology remain to be defined. And because of the multiple phenotypic variation and clinical presentation, the identification of the pathogenic mechanisms remains complicated.
While many patients can be successfully treated (plasma derivatives, corticosteroids, plasma exchange, immunosuppressives treatment) with current therapies, some do not respond or have lasting disability.

In Europe, there are centers of expertise for this type of pathology. EPODIN is mobilized to promote access to the best diagnostic and therapeutic standards throughout Europe.

LSS/MADSAM

Lewis Sumner Syndrome: Multifocal acquired demyelinating sensory and motor neuropathy

GBS

Guillain-Barré Syndrome

Guillain-Barré syndrome is a disorder of the peripheral nerves (see below) characterised by weakness or even progressive paralysis, most often starting in the legs and sometimes progressing to the breathing muscles and then to the nerves in the head and neck. This syndrome is also known as acute inflammatory polyradiculoneuropathy, or acute post-infectious polyradiculoneuropathy, because it often occurs after an infection. In the majority of cases, sufferers recover their physical abilities within 6 to 12 months.

In Europe, there are centers of expertise for this type of pathology. EPODIN is
mobilized to promote access to the best diagnostic and therapeutic standards throughout Europe.

MMN

Multifocal Motor Neuropathies

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Cum sociis natoque penatibus et magnis dis parturient montes, nascetur ridiculus mus. Vestibulum id ligula porta felis euismod semper. Cras justo odio, dapibus ac facilisis in, egestas eget quam. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Sed posuere consectetur est at lobortis.

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MFS

Miller Fisher Syndrome

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Aenean lacinia bibendum nulla sed consectetur.
Cum sociis natoque penatibus et magnis dis parturient montes, nascetur ridiculus mus. Vestibulum id ligula porta felis euismod semper. Cras justo odio, dapibus ac facilisis in, egestas eget quam. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Sed posuere consectetur est at lobortis.

Fusce dapibus, tellus ac cursus commodo, tortor mauris condimentum nibh, ut fermentum massa justo sit amet risus. Nullam id dolor id nibh ultricies vehicula ut id elit. Aenean lacinia bibendum nulla sed consectetur. Maecenas faucibus mollis interdum. Morbi leo risus, porta ac consectetur ac, vestibulum at eros.

Neuropathies

Associated with dysglobulinemia

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Aenean lacinia bibendum nulla sed consectetur.
Cum sociis natoque penatibus et magnis dis parturient montes, nascetur ridiculus mus. Vestibulum id ligula porta felis euismod semper. Cras justo odio, dapibus ac facilisis in, egestas eget quam. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Sed posuere consectetur est at lobortis.

Fusce dapibus, tellus ac cursus commodo, tortor mauris condimentum nibh, ut fermentum massa justo sit amet risus. Nullam id dolor id nibh ultricies vehicula ut id elit. Aenean lacinia bibendum nulla sed consectetur. Maecenas faucibus mollis interdum. Morbi leo risus, porta ac consectetur ac, vestibulum at eros.